BDBM50352577 CHEMBL1825145::US8772288, 29

SMILES CN1CCC2(CC1)C(=O)Nc1cc(ccc21)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=HLQKUQLBVLFLPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50352577   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352577(CHEMBL1825145 | US8772288, 29)
Affinity DataIC50:  5.20nMpH: 7.5 T: 2°CAssay Description:Enzymatic activity assay was performed in 96-well microtiter plates (Corning, catalog number #3686) using a total volume of 50 ul of an assay buffer ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352577(CHEMBL1825145 | US8772288, 29)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of p38alpha in human whole blood assessed as reduction in TNF-alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM50352577(CHEMBL1825145 | US8772288, 29)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed