BDBM50353425 CHEMBL1829740

SMILES Cc1cccc(c1)N1CCC(C)(OC1=O)c1ccccc1

InChI Key InChIKey=YPCOLEPFZYAVIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353425   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50353425(CHEMBL1829740)
Affinity DataIC50: 42nMAssay Description:Inhibition of human 11 beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol after 1 hr by scintillation proximity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50353425(CHEMBL1829740)
Affinity DataIC50: 166nMAssay Description:Inhibition of human 11beta-HSD1 incubated for 22 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50353425(CHEMBL1829740)
Affinity DataIC50: 166nMAssay Description:Inhibition of 11 beta-HSD1 in differentiated human adipocytes assessed as conversion of [3H]-cortisone to [3H]-cortisol after 10 mins by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed