BDBM50354084 CHEMBL1836145

SMILES CCCC[C@H]1NC(=O)C[C@@H]2OC(=O)C[C@H](O)[C@H](NC(=O)[C@@H](CSSCC\C=C\2)NC1=O)[C@@H](C)CC

InChI Key InChIKey=MUNWAZFRKGVMPQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50354084   

TargetHistone deacetylase 1(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant HDAC1 after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC3/NCOR2 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human recombinant HDAC6 after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-L-Lys(epsilon-acetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of recombinant human HDAC4 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant human HDAC7 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human HDAC9 using Boc-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate by two-step fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50354084(CHEMBL1836145)
Affinity DataIC50: 5.74E+4nMAssay Description:Inhibition of human recombinant HDAC4 after 1 hr by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed