BDBM50354421 CHEMBL1836803

SMILES COc1cc(Nc2nc(C)cn3c(cnc23)-c2cn[nH]c2)ccc1C(=O)N1CCNCC1

InChI Key InChIKey=JFIZOYQARFPKTF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50354421   

TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354421(CHEMBL1836803)
Affinity DataIC50: 22nMAssay Description:Inhibition of phosphorylation of SAM68 in 293 WT-PTK6 cells after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354421(CHEMBL1836803)
Affinity DataIC50: 23nMAssay Description:Inhibition of BRK pretreated for 30 mins by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50354421(CHEMBL1836803)
Affinity DataIC50: 837nMAssay Description:Inhibition of AurBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed