BDBM50355353 CHEMBL1835420

SMILES CC(C)(C)OC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CC2(C[C@H]1C(=O)NCCCCCC(=O)NO)SCCS2

InChI Key InChIKey=RGHXCHLVSIEODJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355353   

TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50355353(CHEMBL1835420)
Affinity DataIC50: 140nMAssay Description:Inhibition of human HDAC8 expressed in Escherichia coli using Boc-Lys (acetyl)-AMC as substrate treated for 5 mins before substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50355353(CHEMBL1835420)
Affinity DataIC50: 750nMAssay Description:Inhibition of human HDAC1 expressed in Escherichia coli using fluorogenic substrate treated for 5 mins before substrate addition measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed