BDBM50356674 CHEMBL1917589

SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)c1ccccc1

InChI Key InChIKey=ONUHAMHIYVJDSO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356674   

TargetProstaglandin D2 receptor 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356674(CHEMBL1917589)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356674(CHEMBL1917589)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed