BDBM50356676 CHEMBL1917591

SMILES Cc1ccc(cc1C#Cc1cc(Cl)ccc1OCC(O)=O)S(=O)(=O)CCCO

InChI Key InChIKey=HXFQHYOBBDZAOC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356676   

TargetProstaglandin D2 receptor 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356676(CHEMBL1917591)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 expressed in chinese hamster CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356676(CHEMBL1917591)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at CRTH2 in human blood cells assessed as inhibition of PGD2-induced eosinophil cell shape change after 10 mins by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed