BDBM50356877 CHEMBL1614710

SMILES FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1

InChI Key InChIKey=FGTCROZDHDSNIO-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50356877   

TargetVascular endothelial growth factor receptor 2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 15nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 15nMAssay Description:Inhibition of c-RAF (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 15nMAssay Description:Inhibition of KDR (unknown origin) using peptide as substrate incubated for 90 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 22nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 29nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataIC50: 41nMAssay Description:Inhibition of c-RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50356877(CHEMBL1614710)
Affinity DataKi:  2.40E+4nMAssay Description:Inhibition of human His-tagged CYP3A4 expressed in Escherichia coli TOPP3 using BFC as substrate after 15 mins by double reciprocal plot analysis in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed