BDBM50356930 CHEMBL1914475

SMILES CC(=O)Nc1cn2cc(C=C3SC(O)=NC3=O)ccc2n1

InChI Key InChIKey=CCECKHDWHUIQQG-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356930   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50356930(CHEMBL1914475)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50356930(CHEMBL1914475)Copy SMILESCopy InChI

Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human PI3Kgamma by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50356930(CHEMBL1914475)Copy SMILESCopy InChI

Affinity DataIC50: 760nMAssay Description:Inhibition of PI3Kgamma in human neutrophils assessed as inhibition of fMLP-stimulated superoxide productionMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/21/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL