BDBM50357610 CHEMBL1915644
SMILES CNC(=O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccncc21
InChI Key InChIKey=IXLHWDDKCRTAAT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50357610
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 30 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of PIM1 using KKRNRTLTV as substrate by millipore assay in the presence of 90 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of PIM2 by millipore assay in the presence of 15 uM [ATP]More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of FLT3 using EAIYAAPFAKKK as substrate by radiometric assay in the presence of 200 uM [ATP]More data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+3nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 5 uM [ATP]More data for this Ligand-Target Pair
Affinity DataIC50: 367nMAssay Description:Inhibition of PIM3 using RSRHSSYPAGT as substrate by radiometric assay in the presence of 155 uM [ATP]More data for this Ligand-Target Pair