BDBM50357621 CHEMBL1915673

SMILES CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3C)c(C)c2C)Oc2ccccc12

InChI Key InChIKey=NCSFMOQPIRSCAX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357621   

TargetProstaglandin D2 receptor(Mouse)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357621(CHEMBL1915673)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at mouse prostanoid DP receptor expressed in CHO cells assessed as inhibition of PGD2-induced intracellular cAMP production after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstacyclin receptor(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50357621(CHEMBL1915673)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [3H]Iloprost from human prostanoid IP receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed