BDBM50357850 CHEMBL1916109
SMILES Cc1nc(-c2cccnc2C)n2c1c(C)nc1ccc(cc21)C(F)(F)F
InChI Key InChIKey=FMHQKWMVSBVGPC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50357850
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human PDE2A using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair