BDBM50358055 CHEMBL1914461::US20250353857, Compound JK-367

SMILES Oc1ccc(cc1)-c1cc2c(NCc3ccccc3)ncnc2[nH]1

InChI Key InChIKey=GVGLTLSHSVZGHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358055   

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358055BDBM50358055(CHEMBL1914461 | US20250353857, Compound JK-367)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of EGFR by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50358055BDBM50358055(CHEMBL1914461 | US20250353857, Compound JK-367)
Affinity DataIC50: 200nMAssay Description:The compounds were supplied in a 10 mM DMSO solution, and enzymatic CSF1R inhibition potency was determined by Invitrogen (TermoFisher) using their Z...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2026
Entry Details