BDBM50359206 CHEMBL1923301

SMILES CCN1C(=O)c2nc(-c3ccc(-c4ccccc4)cc3)n(Cc3cccc(F)c3)c2N2C[C@@H](C(C)C)N=C12

InChI Key InChIKey=NYNQTQYAQWZRIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359206   

TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359206BDBM50359206(CHEMBL1923301)
Affinity DataIC50: 269nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed