BDBM50359386 CHEMBL1929411

SMILES Nc1nc2ccccc2nc1C(=O)Nc1ccc(CN2CCCC2)cc1

InChI Key InChIKey=MTDODFSDMGLTDF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359386   

TargetHistamine H3 receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50359386(CHEMBL1929411)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at histamine H3 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50359386(CHEMBL1929411)
Affinity DataIC50: 379nMAssay Description:Antagonist activity at histamine H3 receptor expressed in HEK293 cells co-transfected with pCRE-Luc gene assessed as inhibition of forskolin/histamin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50359386(CHEMBL1929411)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of AChE in rat cortex homogenates using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed