BDBM50359390 CHEMBL1929418::CHEMBL2022924

SMILES CN(CC#C)Cc1cc2cc(OCc3ccccc3)ccc2n1C

InChI Key InChIKey=YASPBSWTXDWFLF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50359390   

TargetAmine oxidase [flavin-containing] B(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat liver mitochondrial MAOB using [14C]-PEA as substrate preincubated for 30 mins followed by substrate addition by liquid scintillati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 63nMAssay Description:Inhibition of mitochondrial MAO-B in rat liver homogenates using [14C]-phenylethylamine as substrate preincubated for 30 mins by liquid scintillation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 100nMAssay Description:Inhibition of mitochondrial MAO-A in rat liver homogenates using [14C]-(5-hydroxy-triptamine) as substrate preincubated for 30 mins by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 100nMAssay Description:Inhibition of rat liver mitochondrial MAOA [14C]-5-HT as substrate preincubated for 30 mins followed by substrate addition by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Laboratorio De Radicales Libres Y Qu�Mica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359390(CHEMBL2022924 | CHEMBL1929418)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed