BDBM50359642 CHEMBL1928875

SMILES Fc1cccc(c1)C1Sc2nncn2N=C1c1ccc2OCC(=O)Nc2c1

InChI Key InChIKey=DFBSMSXIFGLYCG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50359642   

TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50359642(CHEMBL1928875)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]-Aldosterone from human MR overexpressed in FreeStyle 293 cells incubated for 16 hrs by TopCount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50359642(CHEMBL1928875)
Affinity DataIC50: 310nMAssay Description:Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359642(CHEMBL1928875)
Affinity DataIC50: 4.70E+3nMAssay Description:Displacement of [3H]testosterone from ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359642(CHEMBL1928875)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dexomethasone from GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359642(CHEMBL1928875)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]progesterone from PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed