BDBM50360299 CHEMBL1933286::US9150577, 54

SMILES CN(C)CCCn1c(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)nc2ccc(Cl)cc12

InChI Key InChIKey=VCZQSUBZCZZLAX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50360299   

TargetRibosomal protein S6 kinase alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50360299(CHEMBL1933286 | US9150577, 54)
Affinity DataIC50: 20nMAssay Description:Inhibition of human RSK2 in MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50360299(CHEMBL1933286 | US9150577, 54)
Affinity DataIC50: 20nMAssay Description:Inhibition of human RSK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50360299(CHEMBL1933286 | US9150577, 54)
Affinity DataIC50: 20nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50360299(CHEMBL1933286 | US9150577, 54)
Affinity DataIC50: 160nMAssay Description:Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed