BDBM50360459 CHEMBL1934625

SMILES CN(C)Cc1ccc(cc1)C#Cc1c(C)ncnc1Nc1ccc(OCc2cccc(F)c2)c(Cl)c1

InChI Key InChIKey=RRXSXSCXMPQLTP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360459   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360459(CHEMBL1934625)
Affinity DataIC50: 41nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed