BDBM50360465 CHEMBL1934631

SMILES Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1\C=C\c1ccc(CNCCS(C)(=O)=O)cc1

InChI Key InChIKey=BLLJPLGCOYWICB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360465   

TargetEpidermal growth factor receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)
Affinity DataIC50: 94nMAssay Description:Inhibition of EGFR phosphorylation in EGF-stimulated human A431 after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50360465(CHEMBL1934631)
Affinity DataIC50: 120nMAssay Description:Inhibition of Her-2 by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed