BDBM50360494 CHEMBL138662

SMILES COc1ccc(C(=O)\C=C\c2ccc(Cl)cc2)c(OC)c1

InChI Key InChIKey=SIPIMPITDGVGQS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360494   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50360494(CHEMBL138662)Copy SMILESCopy InChI

Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50360494(CHEMBL138662)Copy SMILESCopy InChI

Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL