BDBM50360512 CHEMBL573524

SMILES COc1ccc(\C=C\C(=O)c2ccc(O)cc2O)cc1OC

InChI Key InChIKey=ZMMIEHPFMMRMMN-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360512   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50360512(CHEMBL573524)Copy SMILESCopy InChI

Affinity DataIC50: 850nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50360512(CHEMBL573524)Copy SMILESCopy InChI

Affinity DataIC50: 930nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetAldo-keto reductase family 1 member B1(Rat)TBA

LigandBDBM50360512(CHEMBL573524)Copy SMILESCopy InChI

Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details Article
Copy BDB DOI
Copy reaction URL