BDBM50360513 CHEMBL573523

SMILES COc1cccc(\C=C\C(=O)c2ccc(O)cc2O)c1

InChI Key InChIKey=AACDPQIFRBEZFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360513   

LigandPNGBDBM50360513(CHEMBL573523)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360513(CHEMBL573523)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of BCRP in human MCF7/MX cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by FluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBile acid receptor(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50360513(CHEMBL573523)
Affinity DataIC50: 1.51E+4nMAssay Description:Antagonist activity at GAL4-DBD fused human FXR LBD expressed in HEK293T cells assessed as inhibition of CDCA-induced receptor activation after 24 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed