BDBM50360581 CHEMBL1933344

SMILES CN1C\C=C\CCOc2cccc(c2)-c2nc(Nc3cccc(C1)c3)nc1nc[nH]c21

InChI Key InChIKey=IADKHXRZAFUCSV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50360581   

LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50: 58nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50: 390nMAssay Description:Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50: 390nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50: 450nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed