BDBM50360582 CHEMBL1933345

SMILES Oc1ccc(cc1)-c1nc(Nc2cccc(Cl)c2)nc2nc[nH]c12

InChI Key InChIKey=DVJXBMQCLHDFIV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50360582   

TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 830nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50360582(CHEMBL1933345)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 using RbING as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed