BDBM503606 US11034670, Ex. 46

SMILES CN/C(C#N)=C\C(=N)N1CCN(C(=O)CCc2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=SNIHOQWUMVGWSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503606   

TargetPoly [ADP-ribose] polymerase 1(Human)
Mitobridge

US Patent
LigandChemical structure of BindingDB Monomer ID 503606BDBM503606(US11034670, Ex. 46)
Affinity DataIC50: 278nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2021
Entry Details
US Patent