BDBM50360771 CHEMBL1934650

SMILES NC(=O)c1sc2ncnc(-c3cccc(NC(=O)Nc4ccc(cc4)C(F)(F)F)c3)c2c1N

InChI Key InChIKey=WIXLTAQIFOIEBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360771   

TargetSerine/threonine-protein kinase B-raf(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50360771(CHEMBL1934650)
Affinity DataIC50: 327nMAssay Description:Inhibition of B-Raf in human A375 cells assessed as inhibition of phosphorylation of MEK1/2 by meso scale assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed