BDBM50361010 CHEMBL1935572

SMILES CN1CCN(CC1)c1nc(N)nc2cc(ccc12)-c1ccsc1

InChI Key InChIKey=PRWLDKKWXOINJS-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50361010   

TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361010(CHEMBL1935572)
Affinity DataKi:  3nMAssay Description:Antagonist activity at human H4 receptor expressed in HEK293T cells assessed as inhibition of histamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361010(CHEMBL1935572)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361010(CHEMBL1935572)
Affinity DataIC50: 46nMAssay Description:Antagonist activity at human H4 receptor expressed in HEK293T cells assessed as inhibition of histamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361010(CHEMBL1935572)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361010(CHEMBL1935572)
Affinity DataKi:  2.80E+3nMAssay Description:Displacement of [3H]histamine from human H1 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed