BDBM50361016 CHEMBL501882::US8796297, 13

SMILES CN1CCN(CC1)c1ccnc(N)n1

InChI Key InChIKey=XEKHYAPKOUIALX-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361016   

TargetHistamine H3 receptor(Rat)
Abbvie

US Patent
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  7.41nM ΔG°:  -10.3kcal/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetHistamine H3 receptor(Human)
Abbvie

US Patent
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  13.8nM ΔG°:  -9.96kcal/molepH: 7.4 T: 2°CAssay Description:The rat H3 receptor was cloned and expressed in cells, and competition binding assays carried out, according to methods previously described (see Esb...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent

TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361016(CHEMBL501882 | US8796297, 13)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed