BDBM50361158 CHEMBL4162429

SMILES CN(C)[C@H]1C[C@@]23CC[C@]4(O2)C2CC=C(c5ccc6ccncc6c5)[C@@]2(C)CC=C4C=C3[C@@H](O)[C@@H]1O

InChI Key InChIKey=HSNLDXFFYGOHED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361158   

TargetCyclin-dependent kinase 8(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50361158(CHEMBL4162429)
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK8 in human HepG2 cells assessed as reduction in IFNgamma-induced STAT1 phosphorylation at S727 measured after 18 hrs by Western blot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed