BDBM50361196 CHEMBL1934327

SMILES CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5cccc(F)c5)cc4)ncnc3c2)CC1

InChI Key InChIKey=KCVMRCBFSCVBTH-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50361196   

TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50361196(CHEMBL1934327)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed