BDBM50361846 CHEMBL1938794::US9150577, 15

SMILES O=C(Nc1cn[nH]c1)c1ccc2cc3C(=O)NCCCn3c2c1

InChI Key InChIKey=ULNZFQKAFXCYBO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361846   

TargetRibosomal protein S6 kinase alpha-2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50361846(CHEMBL1938794 | US9150577, 15)
Affinity DataIC50: 43nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361846(CHEMBL1938794 | US9150577, 15)
Affinity DataIC50: 43nMAssay Description:Inhibition of RSK2 phosphorylation by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361846(CHEMBL1938794 | US9150577, 15)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RSK2-mediated CREB phosphorylation in HeLa cells expressing luciferase reporter geneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed