BDBM50361854 CHEMBL1938767::US9150577, 151

SMILES C[C@@H]1CNC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cccnc1

InChI Key InChIKey=DUPMGAVJLVBVOW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361854   

TargetRibosomal protein S6 kinase alpha-3(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361854(CHEMBL1938767 | US9150577, 151)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of RSK2 phosphorylation by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM50361854(CHEMBL1938767 | US9150577, 151)
Affinity DataIC50: 1.10E+3nMpH: 7.5Assay Description:Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2016
Entry Details
US Patent