BDBM50362408 CHEMBL1940142

SMILES Cc1nccn1-c1nc(nc(n1)-c1ccc(C)c2[nH]ccc12)N1CCOCC1

InChI Key InChIKey=JNFCYFOVXWKHNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362408   

TargetSerine/threonine-protein kinase mTOR(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50362408(CHEMBL1940142)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50362408(CHEMBL1940142)
Affinity DataIC50: 84nMAssay Description:Inhibition of mTOR-mediated p70S6K phosphorylation at Thr389 in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50362408(CHEMBL1940142)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed