BDBM50362901 CHEMBL1945285

SMILES CC(C)Cc1ccc(cc1)[C@H](CF)C(O)=O

InChI Key InChIKey=RHYPLXHTNFTLQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362901   

TargetProstaglandin G/H synthase 1(Human)
Shanghai Haini Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362901(CHEMBL1945285)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of COX1 in human HEL 92.1.7 cells assessed as thromboxane B2 production incubated for 30 mins before arachidonic acid addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Shanghai Haini Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362901(CHEMBL1945285)
Affinity DataIC50: 500nMAssay Description:Inhibition of ovine COX1 by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Shanghai Haini Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362901(CHEMBL1945285)
Affinity DataIC50: 530nMAssay Description:Inhibition of COX2 in LPS-stimulated and PMA-treated human U937 cells assessed as PGE2 production after 15 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed