BDBM50362965 CHEMBL1947140

SMILES COc1ccc2c(-n3c(=O)n(Cc4cccc([C@@]5(C)OC(O)=NC5=O)c4)c4cc(C(F)(F)F)ccc43)noc2c1

InChI Key InChIKey=FOJNEKOFXMOJEI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362965   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362965BDBM50362965(CHEMBL1947140)
Affinity DataIC50: 93nMAssay Description:Binding affinity to human PPARgamma by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362965BDBM50362965(CHEMBL1947140)
Affinity DataEC50:  237nMAssay Description:Agonist activity at human PPARgamma expressed in COS-1 cells co-expressing with Gal4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362965BDBM50362965(CHEMBL1947140)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to human PPARalpha expressed in COS-1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50362965BDBM50362965(CHEMBL1947140)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity to PPARdelta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed