BDBM50363199 CHEMBL1946150

SMILES CCS(=O)(=O)CNc1cc2CN(C)C\C=C\CCOc3cccc(c3)-c3ccnc(Nc(c2)c1)n3

InChI Key InChIKey=HZRJYORBAMJSIQ-SNAWJCMRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363199   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363199(CHEMBL1946150)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363199(CHEMBL1946150)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50363199(CHEMBL1946150)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed