BDBM50363211 CHEMBL1947162

SMILES C1C\C=C\CNCc2cccc(Nc3nccc(n3)-c3cccc(O1)c3)c2

InChI Key InChIKey=JEMMIJOETMAKME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363211   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50363211(CHEMBL1947162)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50363211(CHEMBL1947162)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50363211(CHEMBL1947162)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed