BDBM50363233 CHEMBL1945707

SMILES CN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3ccc(OCCN4CCCCC4)c(C1)c3)n2

InChI Key InChIKey=GOWRQMXPMZRPRM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363233   

LigandPNGBDBM50363233(CHEMBL1945707)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant Flt3 using poly(Glu,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50363233(CHEMBL1945707)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
S Bio

Curated by ChEMBL
LigandPNGBDBM50363233(CHEMBL1945707)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant Cdk2/cyclin A using RbING as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed