BDBM50363269 CHEMBL1944724

SMILES O=c1cc(CN(Cc2ccccc2F)c2cnccn2)c2ccc(F)c(F)c2[nH]1

InChI Key InChIKey=RNBQLEGGGJNBRQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363269   

TargetNitric oxide synthase, inducible(Human)
Afraxis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363269BDBM50363269(CHEMBL1944724)
Affinity DataIC50: 12nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Afraxis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363269BDBM50363269(CHEMBL1944724)
Affinity DataIC50: 64nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Afraxis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50363269BDBM50363269(CHEMBL1944724)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed