BDBM50363453 CHEMBL1946331

SMILES CC(C)Nc1ncc2nc(Nc3ccccc3F)n(C3CCCC3)c2n1

InChI Key InChIKey=KEJPODFMUKBEAK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363453   

TargetMitogen-activated protein kinase 9(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50: 66nMAssay Description:Inhibition of full length Hexa-His-tagged JNK2 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50: 110nMAssay Description:Inhibition of full length Hexa-His-tagged JNK3 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50: 800nMAssay Description:Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50363453(CHEMBL1946331)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of p38alpha using MBP and [gamma33P]ATP as substrate after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed