BDBM50363493 3,4,6-tribromo-5-(2,5-dibromo-3,4-dihydroxybenzyl)benzene-1,2-diol (3)::CHEMBL464987

SMILES Oc1c(O)c(Br)c(Cc2c(Br)c(O)c(O)c(Br)c2Br)cc1Br

InChI Key InChIKey=CVTMBOIHOUULML-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50363493   

TargetAldo-keto reductase family 1 member B1(Human)
Jilin Province Academy of Traditional Chinese Medicine and Materia Medica

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataIC50: 638nMAssay Description:Inhibition of human muscle recombinant aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataKi:  1.74E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataKi:  2.12E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataKi:  2.75E+4nMAssay Description:Inhibition of human carbonic anhydrase 4 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataKi:  3.44E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363493(CHEMBL464987 | 3,4,6-tribromo-5-(2,5-dibromo-3,4-d...)
Affinity DataIC50: 8.64E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed