BDBM50363798 CHEMBL1947108

SMILES Oc1ccc2oc(=O)c3[nH]c4cccc(c4c3c2c1)C(F)(F)F

InChI Key InChIKey=AIDSJCIQTLHYSQ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363798   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Orleans University

Curated by ChEMBL

LigandBDBM50363798(CHEMBL1947108)Copy SMILESCopy InChI

Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate and [gamma-33P]ATP after 30 min...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetCyclin-dependent kinase 5 activator 1(Human)
Orleans University

Curated by ChEMBL

LigandBDBM50363798(CHEMBL1947108)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using [gamma-33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL