BDBM50363958 CHEMBL1952211

SMILES COc1ccc(cc1)N1Cc2cnc(Nc3ccccc3)nc2N([C@H]2CC[C@H](O)C2)C1=O

InChI Key InChIKey=NDEFXZOKPREYOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363958   

TargetVascular endothelial growth factor receptor 2(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363958(CHEMBL1952211)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant EE-tagged intracellular domain of KDR using biotin-EEEEYFELVAKKKK as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50363958(CHEMBL1952211)
Affinity DataIC50: 365nMAssay Description:Inhibition of human recombinant His-tagged intracellular domain of EGFR using biotin-EEEEYFELV as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed