BDBM50364014 CHEMBL1950402

SMILES OC(=O)Cc1cncc(c1)-c1ccc(nn1)N1CCC(CC1)Oc1cc(F)ccc1Br

InChI Key InChIKey=QRBORTBSPFTFBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50364014   

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364014(CHEMBL1950402)
Affinity DataIC50: 20nMAssay Description:Inhibition of rat SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364014(CHEMBL1950402)
Affinity DataIC50: 75nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat hepatocytes assessed as conversion of [14C]oleic acid formation by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364014(CHEMBL1950402)
Affinity DataIC50: 780nMAssay Description:Inhibition of human SCD1 expressed in human HepG2 cells assessed as conversion of [14C]stearic acid to [14C]oleic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed