BDBM50364375 CHEMBL1950302

SMILES CC(C)(O)[C@H]1CC[C@H](C1)c1ncc2nc(Nc3ccc(F)cc3F)n(C3CCOCC3)c2n1

InChI Key InChIKey=JPJFWEVMWXMYLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364375   

TargetMitogen-activated protein kinase 8(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364375(CHEMBL1950302)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364375(CHEMBL1950302)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of p38alpha using myelin basic protein as substrate preincubated for 15 mins prior ATP addition measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed