BDBM50364406 CHEMBL1950445
SMILES C[C@H](NC(=O)[C@@H](N)[C@@H](C)c1ccc(cc1)-c1ccccc1)c1nc2cc(Cl)c(Cl)cc2[nH]1
InChI Key InChIKey=VAZZKCHOLHYDOP-NPGVVQFXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50364406
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 638nMAssay Description:Inhibition of PrCP-mediated angiotensin3 cleavage in mouse plasma using Mca-Ala-Lys-Dnp as substrate for 8 mins by LC/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of mouse recombinant PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate for 30 mins by continuous fluorimetric assayMore data for this Ligand-Target Pair