BDBM50364426 CHEMBL1950567

SMILES OC(=O)CCC(=O)Nc1ccc(-c2nc3ccc(nc3s2)C2(CC2)c2ccccc2)c(F)c1

InChI Key InChIKey=RNJUDXBXJHLETI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364426   

TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364426(CHEMBL1950567)
Affinity DataEC50:  19nMAssay Description:Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364426(CHEMBL1950567)
Affinity DataEC50:  5.56E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing chimeric Gq/i5 G-protein assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed