BDBM50364664 CHEMBL1951453

SMILES CCCOc1sc(C(=O)N2CCC(CC2)c2cccc(CN)c2)c(C)c1Br

InChI Key InChIKey=UAGMQELKQICEOO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50364664   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364664(CHEMBL1951453)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERG by whole-cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364664(CHEMBL1951453)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human CYP2D6 using dexotromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364664(CHEMBL1951453)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human CYP3A4 using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed