BDBM50365490 CHEMBL1957377

SMILES Oc1c(C#N)c(nc2ccncc12)-c1ccc(cc1)-c1ccccc1CN1CCOCC1

InChI Key InChIKey=HXUBMJGKOWFRSA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365490   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50365490(CHEMBL1957377)Copy SMILESCopy InChI

Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/23/2012
Entry Details Article
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